Nicole Holofcener has trouble breathing. She finds herself holding her breath for too long, which could be a result of allergies or a byproduct of sleep apnea. But it’s also an apt metaphor for the life of an independent filmmaker. Nicole and Marc talk about what it takes to make films with small budgets, casting conundrums, and deeply personal subject matter. They discuss the films she wrote and directed like Walking and Talking, Lovely and Amazing, and Enough Said, as well as her contributions to The Last Duel and her reasons for continuing to work on episodic television shows.